Timeout exception in log

Spelunking through the Datomic logs, I have come across many instances of the message below. Is there anything to be concerned about?

{
    "Msg": "Cache put-result-handler error: net.spy.memcached.internal.CheckedOperationTimeoutException: Operation timed out. - failing node: /10.213.1.121:11211",
    "Ex": {
        "Cause": "Operation timed out. - failing node: /10.213.1.121:11211",
        "Via": [
            {
                "Type": "java.util.concurrent.ExecutionException",
                "Message": "net.spy.memcached.internal.CheckedOperationTimeoutException: Operation timed out. - failing node: /10.213.1.121:11211",
                "At": [
                    "net.spy.memcached.internal.OperationFuture",
                    "get",
                    "OperationFuture.java",
                    180
                ]
            },
            {
                "Type": "net.spy.memcached.internal.CheckedOperationTimeoutException",
                "Message": "Operation timed out. - failing node: /10.213.1.121:11211",
                "At": [
                    "net.spy.memcached.internal.OperationFuture",
                    "get",
                    "OperationFuture.java",
                    180
                ]
            }
        ],
        "Trace": [
            [
                "net.spy.memcached.internal.OperationFuture",
                "get",
                "OperationFuture.java",
                180
            ],
            [
                "net.spy.memcached.internal.OperationFuture",
                "get",
                "OperationFuture.java",
                140
            ],
            [
                "clojure.core$deref_future",
                "invokeStatic",
                "core.clj",
                2292
            ],
            [
                "clojure.core$deref",
                "invokeStatic",
                "core.clj",
                2312
            ],
            [
                "clojure.core$deref",
                "invoke",
                "core.clj",
                2298
            ],
            [
                "datomic.mc_cache$safe_deref",
                "invokeStatic",
                "mc_cache.clj",
                91
            ],
            [
                "datomic.mc_cache$safe_deref",
                "invoke",
                "mc_cache.clj",
                89
            ],
            [
                "datomic.mc_cache$put_result_handler",
                "invokeStatic",
                "mc_cache.clj",
                124
            ],
            [
                "datomic.mc_cache$put_result_handler",
                "invoke",
                "mc_cache.clj",
                122
            ],
            [
                "datomic.mc_cache$wrap_metrics$fn__20916",
                "invoke",
                "mc_cache.clj",
                44
            ],
            [
                "datomic.mc_cache$op_listener$reify__20923",
                "onComplete",
                "mc_cache.clj",
                78
            ],
            [
                "net.spy.memcached.internal.AbstractListenableFuture$1",
                "run",
                "AbstractListenableFuture.java",
                117
            ],
            [
                "java.util.concurrent.Executors$RunnableAdapter",
                "call",
                "Executors.java",
                511
            ],
            [
                "java.util.concurrent.FutureTask",
                "run",
                "FutureTask.java",
                266
            ],
            [
                "java.util.concurrent.ThreadPoolExecutor",
                "runWorker",
                "ThreadPoolExecutor.java",
                1149
            ],
            [
                "java.util.concurrent.ThreadPoolExecutor$Worker",
                "run",
                "ThreadPoolExecutor.java",
                624
            ],
            [
                "java.lang.Thread",
                "run",
                "Thread.java",
                748
            ]
        ]
    },
    "Type": "Event",
    "Tid": 5653,
    "Timestamp": 1532657773211
}

We are seeing the same thing in Datomic Cloud. Wondering if it is important …